Synvisc is an FDA-approved local therapy that provides lubrication for your knee and acts as a “shock absorber” to cushion your knee joint. Synvisc is made from a substance called hyaluronan which is found in normal joint fluid. Hyaluronan, which acts as a “shock absorber” and lubricant in your knee joint, is needed for your joint to work properly. Synvisc is a pill-free treatment; it is an elastic and viscous fluid that is injected directly into the knee joint. Successful treatment with Synvisc can help reduce osteoarthritis knee pain, which can lead to increased mobility. Pain relief can last for up to 6 months. While you may begin to feel some relief right away, most patients feel greatest pain relief 8 to 12 weeks after beginning treatment. (Note: Your doctor may ask you to temporarily avoid strenuous activity after treatment.) To learn more about Synvisc, click here .